Nov 3, 2022 · 11:06 PM UTC · Twitter Web App
Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)...
Background: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed great threat to human health. T cells play a critical...pubmed.ncbi.nlm.nih.gov
(PDF) AIDS and COVID-19 are two diseases separated by a common lymphocytopenia
PDF | HIV and SARS-CoV-2 are responsible for two of the most dangerous and life-threatening infectious diseases of our times. To better analyze the... | Find, read and cite all the research you need...researchgate.net
Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire...
Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 is a newly recognized condition in children with recent severe acute...pnas.org
Immune suppression in the early stage of COVID-19 disease
Nature Communications - How COVID-19 pathology differs from other drivers of pneumonia is unclear. Here the authors analyze urine from patients with COVID-19 and identify an immunosuppressive...nature.com
Akt-Fas to Quell Aberrant T Cell Differentiation and Apoptosis in Covid-19
Aberrant T cell differentiation and lymphopenia are hallmarks of severe COVID-19 disease. Since T cells must race to cull infected cells, they are quick to differentiate and achieve cytotoxic...ncbi.nlm.nih.gov
SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 express...
Signal Transduction and Targeted Therapy - SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolismnature.com
Uncertainty around the Long-Term Implications of COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 231 million people globally, with more than 4.7 million deaths recorded by the World Health Organization as of 26...mdpi.com
Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2...
Nature Immunology - Phetsouphanh and colleagues show that individuals with long COVID have persistent activation of the innate and adaptive immune system at 8 months after infection and define a...nature.com
Understanding the Effects of Age and T-Cell Differentiation on COVID-19 Severity: Implicating a...
Abstract Fas expression is quickly upregulated on CD8+ T cells following stimulation, while FasL expression is limited to Tcm and Tem.1 A phenomenon of T cell effector differentiation via paracrine...frontiersin.org
The immunology and immunopathology of COVID-19
Considerable research effort has been made worldwide to decipher the immune response triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, identify the drivers of...science.org
Superantigens and SARS-CoV-2
It has been posited SARS-CoV-2 contains at least one unique superantigen-like motif not found in any other SARS or endemic coronaviruses. Superantigens are potent antigens that can send the immune...mdpi.com
ACE2-independent infection of T lymphocytes by SARS-CoV-2
Signal Transduction and Targeted Therapy - ACE2-independent infection of T lymphocytes by SARS-CoV-2nature.com
T‐cell recovery and evidence of persistent immune activation 12 months after severe COVID‐19
In a multicentric cohort of 173 COVID-19 patients followed-up to 1 year we found evidence of functional and numeric T cell recovery. COVID-19 patients showed persistent moderate T cell activation at...onlinelibrary.wiley.com
Postacute COVID-19 is Characterized by Gut Viral Antigen Persistence in Inflammatory Bowel Diseases
The coronavirus disease 2019 (COVID-19) pandemic has affected populations, societies, and lives for more than 2 years. Long-term sequelae of COVID-19, collectively termed the postacute COVID-19...ncbi.nlm.nih.gov
Reduced Cell Surface Levels of C-C Chemokine Receptor 5 and Immunosuppression in Long Coronavirus...
Abstract. In an exploratory trial treating “long COVID” with the CCR5-binding antibody leronlimab, we observed significantly increased blood cell surface CCR5 iacademic.oup.com
In Cleveland and beyond researchers begin to unravel the mystery of long COVID-19
HIV researchers who have made the crossover to studying long COVID-19 are finding unmistakable similarities, but coronaviruses are not retroviruses like HIV, nor are they sexually transmitted like...cleveland.com
Longitudinal Analysis of COVID-19 Patients Shows Age-Associated T Cell Changes Independent of...
ObjectivesThe immunological and inflammatory changes following acute COVID-19 are hugely variable. Persistent clinical symptoms following resolution of initial infection, termed long COVID, are also...frontiersin.org
"Immunity Debt"? Established 2021
The term didn't exist before 2021counterdisinformationproject.substack.com
T cell apoptosis characterizes severe Covid-19 disease
Cell Death & Differentiation - T cell apoptosis characterizes severe Covid-19 diseasenature.com